Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02622
Species: Mus musculus
Position : chr7:45416017-45418912
Year: 2024
Title: An i-motif-regulated enhancer, eRNA and adjacent lncRNA affect Lhb expression through distinct mechanisms in a sex-specific context.
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
PMID:  39158745
Tissue: pituitary gland
Tissue Ontology ID: UBERON:0000007
Cell Source: Primary pituitary gonadotrope-derived cells from male and female mice
Cell Type: gonadotrope
Experiment Type: Enhancer-associated eRNA validation; Physiological regulatory assay
High Throughput Method: snATAC-seq reanalysis
Low Throughput Method: RT-qPCR; chromatin-associated RNA fractionation
About Target Gene
Target gene : Lhb
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 2 found
Enhancer ID Position Tissue Cell Disease
E_02467 chr7:45416017-45418912 pituitary gland gonadotrope NA
E_02620 chr7:45416017-45418912 pituitary gland gonadotrope NA
Expression of Target Genes for the Enhancer