Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02593
Species: Mus musculus
Position : chr2:10136078-10138078
Year: 2016
Title: Lineage-affiliated transcription factors bind the Gata3 Tce1 enhancer to mediate lineage-specific programs.
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
PMID:  26808502
Tissue: blood / hematopoietic system
Tissue Ontology ID: UBERON:0000178
Cell Source: T Cell
Cell Type: T cell
Cell Ontology ID: CL:0000084
Experiment Type: Enhancer activity assay; TF-binding/chromatin assay; Endogenous enhancer perturbation; In vivo functional validation
Low Throughput Method: CRISPR-Cas9 targeted editing/deletion; ChIP-qPCR/ChIP
About Target Gene
Target gene : Gata3
About TF
TF name : Tcf12
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Tcf12 CDO in myogenesis reactome 29
Tcf12 ID netpath 38
Enhancer Associated Network
Overlapping Enhancers (mm10) 2 found
Enhancer ID Position Tissue Cell Disease
E_02592 chr2:10136078-10138078 blood / hematopoietic system T cell NA
E_02594 chr2:10136078-10138078 blood / hematopoietic system T cell NA
Expression of Target Genes for the Enhancer