About Enhancer
| Enhancer ID: | E_02584 |
| Species: | Mus musculus |
| Position : | chr6:127030000-127032000   |
| Year: | 2018 |
| Title: | A Novel Distal Enhancer Mediates Inflammation-, PTH-, and Early Onset Murine Kidney Disease-Induced Expression of the Mouse Fgf23 Gene. |
| Genome Build: | mm9 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | chronic kidney disease |
| PMID: | 29527594 |
| MONDO: | MONDO:0005300 |
| Tissue: | bone tissue |
| Tissue Ontology ID: | UBERON:0002481 |
| Cell Source: | IDG-SW3 |
| CVCL ID: | CVCL_0P23 |
| Cell Type: | osteoblast |
| Cell Ontology ID: | CL:0000062 |
| Experiment Type: | Candidate enhancer identification; Epigenomic profiling; Endogenous enhancer perturbation; Chromatin-state profiling; In vivo functional validation |
| High Throughput Method: | Histone modification ChIP-seq; ChIP-seq |
| Low Throughput Method: | CRISPR-Cas9 endogenous deletion/editing; ChIP; Mouse genetic deletion/knock-in |
About Target Gene
| Target gene : | Fgf23 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (mm9)
No overlapping enhancers found in mm9 at this locus.
Expression of Target Genes for the Enhancer