About Enhancer
| Enhancer ID: | E_02551 |
| Species: | Mus musculus |
| Position : | chr11:32150550-32151858   |
| Year: | 2025 |
| Title: | The ζ±-globin super-enhancer acts in an orientation-dependent manner. |
| Genome Build: | mm9 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 39863595 |
| Cell Source: | ES-E14TG2a |
| CVCL ID: | CVCL_9108 |
| Cell Type: | primitive erythroid lineage cell |
| Cell Ontology ID: | CL:0002417 |
| Experiment Type: | Enhancer activity assay; TF binding assay; Functional perturbation assay |
| High Throughput Method: | ATAC-seq; published erythroid Gata1 ChIP-seq |
| Low Throughput Method: | CRISPR-Cas9 R2 inversion; RT-qPCR |
About Target Gene
| Target gene : | Hba-a1 |
About TF
| TF name : | Gata1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Gata1 | C-MYB transcription factor network | pid | 87 |
| Gata1 | Factors involved in megakaryocyte development and platelet production | reactome | 111 |
| Gata1 | IL3 | netpath | 84 |
| Gata1 | Notch-mediated HES/HEY network | pid | 48 |
| Gata1 | p73 transcription factor network | pid | 80 |
| Gata1 | Signaling events mediated by HDAC Class I | pid | 89 |
| Gata1 | Signaling events mediated by HDAC Class II | pid | 58 |
Enhancer Associated Network
Overlapping Enhancers (mm9)
44 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_02494 | chr11:32145540-32169344 | NA | primitive erythroid lineage cell | NA |
| E_02495 | chr11:32145540-32169344 | NA | primitive erythroid lineage cell | NA |
| E_00076 | chr11:32150550-32151858 | liver | erythroblast | NA |
| E_00077 | chr11:32150550-32151858 | liver | erythroblast | NA |
| E_00078 | chr11:32150550-32151858 | liver | erythroblast | NA |
| E_00079 | chr11:32150550-32151858 | liver | erythroblast | NA |
| E_00080 | chr11:32150550-32151858 | liver | erythroblast | NA |
| E_00081 | chr11:32150550-32151858 | liver | erythroblast | NA |
| E_00082 | chr11:32150550-32151858 | liver | erythroblast | NA |
| E_00083 | chr11:32150550-32151858 | liver | erythroblast | NA |
| E_00092 | chr11:32150550-32151858 | liver | erythroblast | NA |
| E_00093 | chr11:32150550-32151858 | liver | erythroblast | NA |
| E_00094 | chr11:32150550-32151858 | liver | erythroblast | NA |
| E_00095 | chr11:32150550-32151858 | liver | erythroblast | NA |
| E_00096 | chr11:32150550-32151858 | liver | erythroblast | NA |
| E_00097 | chr11:32150550-32151858 | liver | erythroblast | NA |
| E_00098 | chr11:32150550-32151858 | liver | erythroblast | NA |
| E_00099 | chr11:32150550-32151858 | liver | erythroblast | NA |
| E_00213 | chr11:32150550-32151858 | liver | erythroblast | NA |
| E_00214 | chr11:32150550-32151858 | liver | erythroblast | NA |
| E_00215 | chr11:32150550-32151858 | liver | erythroblast | NA |
| E_00216 | chr11:32150550-32151858 | liver | erythroblast | NA |
| E_00217 | chr11:32150550-32151858 | liver | erythroblast | NA |
| E_00218 | chr11:32150550-32151858 | liver | erythroblast | NA |
| E_00219 | chr11:32150550-32151858 | liver | erythroblast | NA |
| E_00220 | chr11:32150550-32151858 | liver | erythroblast | NA |
| E_00446 | chr11:32150550-32151858 | blood | erythroid cell | NA |
| E_00447 | chr11:32150550-32151858 | blood | erythroid cell | NA |
| E_00448 | chr11:32150550-32151858 | blood | erythroid cell | NA |
| E_00449 | chr11:32150550-32151858 | blood | erythroid cell | NA |
| E_02552 | chr11:32150550-32151858 | NA | primitive erythroid lineage cell | NA |
| E_02553 | chr11:32150550-32151858 | NA | primitive erythroid lineage cell | NA |
| E_02554 | chr11:32150550-32151858 | NA | primitive erythroid lineage cell | NA |
| E_02555 | chr11:32150550-32151858 | NA | primitive erythroid lineage cell | NA |
| E_02556 | chr11:32150550-32151858 | NA | primitive erythroid lineage cell | NA |
| E_02557 | chr11:32150550-32151858 | NA | primitive erythroid lineage cell | NA |
| E_02558 | chr11:32150550-32151858 | NA | primitive erythroid lineage cell | NA |
| E_03313 | chr11:32150550-32151858 | liver | erythroid cell | NA |
| E_03480 | chr11:32150550-32151858 | spleen | erythroblast | NA |
| E_03481 | chr11:32150550-32151858 | spleen | erythroblast | NA |
| E_03482 | chr11:32150550-32151858 | spleen | erythroblast | NA |
| E_03483 | chr11:32150550-32151858 | spleen | erythroblast | NA |
| E_03484 | chr11:32150550-32151858 | spleen | erythroblast | NA |
| E_03485 | chr11:32150550-32151858 | spleen | erythroblast | NA |
Expression of Target Genes for the Enhancer