About Enhancer
| Enhancer ID: | E_02484 |
| Species: | Mus musculus |
| Position : | chr5:9037806-9041881   |
| Year: | 2017 |
| Title: | A class of circadian long non-coding RNAs mark enhancers modulating long-range circadian gene regulation. |
| Genome Build: | mm10 |
| Enhancer Type: | Super-enhancer |
| Condition: | Normal |
| PMID: | 28335007 |
| Tissue: | liver |
| Tissue Ontology ID: | UBERON:0002107 |
| Cell Source: | Liver |
| Experiment Type: | TF-binding/chromatin assay; Chromatin interaction assay; Endogenous enhancer perturbation |
| High Throughput Method: | ChIP-seq; RNA-seq |
| Low Throughput Method: | CRISPR-Cas9 targeted editing/deletion; ChIP-qPCR/ChIP; 4C; RT-qPCR/qPCR |
About Target Gene
| Target gene : | Gm40264 |
About TF
| TF name : | Arntl |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Arntl | BMAL1:CLOCK,NPAS2 activates circadian gene expression | reactome | 42 |
| Arntl | Circadian Clock | reactome | 49 |
| Arntl | Circadian clock system | panther | 9 |
| Arntl | Circadian rhythm pathway | pid | 17 |
| Arntl | NR1D1 (REV-ERBA) represses gene expression | reactome | 8 |
| Arntl | PPARA activates gene expression | reactome | 113 |
| Arntl | RORA activates gene expression | reactome | 27 |
| Arntl | Circadian rhythm - mammal | kegg | 19 |
| Arntl | Circadian rhythm - fly | kegg | 7 |
| Arntl | Hs_Selenium_Metabolism_and_Selenoproteins_WP28_71888 | wikipathways | 9 |
| Arntl | Hs_Hedgehog_Signaling_Pathway_WP47_78542 | wikipathways | 6 |
Enhancer Associated Network
Expression of Target Genes for the Enhancer