Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02472
Species: Mus musculus
Position : chr11:97938123-97980122
Year: 2022
Title: A fast Myosin super enhancer dictates muscle fiber phenotype through competitive interactions with Myosin genes.
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
PMID:  35210422
Tissue: skeletal muscle tissue
Tissue Ontology ID: UBERON:0001134
Cell Source: Myofibers
Cell Type: skeletal muscle myofiber
Experiment Type: Chromatin interaction assay, Functional perturbation assay, Enhancer activity assay
High Throughput Method: ATAC-seq, 4C-seq; RNA-seq; ATAC-seq; 4C-seq; 4C
Low Throughput Method: CRISPR knockout; Transgenic reporter assay; RT-RT-qPCR; CRISPR-Cas9
About Target Gene
Target gene : Myh8
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 4 found
Enhancer ID Position Tissue Cell Disease
E_02468 chr11:97938123-97980122 skeletal muscle tissue skeletal muscle myofiber NA
E_02469 chr11:97938123-97980122 skeletal muscle tissue skeletal muscle myofiber NA
E_02470 chr11:97938123-97980122 skeletal muscle tissue skeletal muscle myofiber NA
E_02471 chr11:97938123-97980122 skeletal muscle tissue skeletal muscle myofiber NA
Expression of Target Genes for the Enhancer