About Enhancer
| Enhancer ID: | E_02432 |
| Species: | Mus musculus |
| Position : | chr17:44464986-44466986   |
| Year: | 2014 |
| Title: | Dlx5 and mef2 regulate a novel runx2 enhancer for osteoblast-specific expression. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 24692107 |
| Cell Source: | Osteoblast-Specific Cell |
| Experiment Type: | Enhancer activity assay; TF-binding/chromatin assay; In vivo functional validation |
| Low Throughput Method: | Luciferase reporter assay; Reporter assay; ChIP-qPCR/ChIP; EMSA/gel-shift assay; Transgenic/LacZ assay |
About Target Gene
| Target gene : | Runx2 |
About TF
| TF name : | Sox6 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Sox6 | Deactivation of the beta-catenin transactivating complex | reactome | 42 |
| Sox6 | Hs_Endochondral_Ossification_WP474_87977 | wikipathways | 43 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
6 found
Expression of Target Genes for the Enhancer