About Enhancer
| Enhancer ID: | E_02330 |
| Species: | Mus musculus |
| Position : | chr13:53463266-53463541   |
| Year: | 2011 |
| Title: | Conserved regulatory motifs in osteogenic gene promoters integrate cooperative effects of canonical Wnt and BMP pathways. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 20878775 |
| Tissue: | blood / hematopoietic system |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | C2C12,Primary Bone Marrow每Mesenchymal Stem Cell |
| Experiment Type: | Enhancer activity assay; TF-binding/chromatin assay; In vivo functional validation |
| Low Throughput Method: | Luciferase reporter assay; Reporter assay; ChIP-qPCR/ChIP; RT-qPCR/qPCR |
About Target Gene
| Target gene : | Msx2 |
About TF
| TF name : | Sp7 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Sp7 | Hs_Role_of_Osx_and_miRNAs_in_tooth_development_WP3971_91525 | wikipathways | 9 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
5 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_02325 | chr13:53463266-53463541 | blood / hematopoietic system | NA | NA |
| E_02326 | chr13:53463266-53463541 | blood / hematopoietic system | NA | NA |
| E_02327 | chr13:53463266-53463541 | blood / hematopoietic system | NA | NA |
| E_02328 | chr13:53463266-53463541 | blood / hematopoietic system | NA | NA |
| E_02329 | chr13:53463266-53463541 | blood / hematopoietic system | NA | NA |
Expression of Target Genes for the Enhancer