Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02290
Species: Mus musculus
Position : chr16:17253000-17253100
Year: 2021
Title: Diet-dependent natriuretic peptide receptor C expression in adipose tissue is mediated by PPAR污 via long-range distal enhancers.
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Disease
Disease Name: obesity
PMID:  34245781
MONDO: MONDO:0011122
Tissue: adipose tissue
Tissue Ontology ID: UBERON:0001013
Cell Source: 3T3-L1
CVCL ID: CVCL_0123
Cell Type: adipocyte
Cell Ontology ID: CL:0000136
Experiment Type: Enhancer activity assay, Chromatin interaction assay, Functional perturbation assay; Enhancer activity assay
High Throughput Method: ChIP-seq
Low Throughput Method: Luciferase Reporter Assay, 3C, ChIP-RT-qPCR, RT-RT-qPCR; Luciferase reporter assay; siRNA knockdown; Reporter assay
About Target Gene
Target gene : Npr3
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer