Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02283
Species: Mus musculus
Position : chr18:61108475-61108975
Year: 2019
Title: Deletion of a Csf1r enhancer selectively impacts CSF1R expression and development of tissue macrophage populations.
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
PMID:  31324781
Tissue: multiple tissues
Cell Source: Csf1r enhancer-deletion mouse
Cell Type: macrophage
Cell Ontology ID: CL:0000235
Experiment Type: Canonical Csf1r FIRE enhancer; current mm10 interval standardized to chr18:61108475-61108975; in vivo FIRE deletion phenotype
High Throughput Method: RNA-seq and macrophage population profiling
Low Throughput Method: Enhancer genome editing mouse; flow cytometry; immunohistochemistry; expression analysis
About Target Gene
Target gene : Csf1r
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 3 found
Enhancer ID Position Tissue Cell Disease
E_02268 chr18:61108475-61108975 embryo macrophage NA
E_02269 chr18:61108475-61108975 skin of body macrophage NA
E_03424 chr18:61108475-61108975 bone marrow B cell NA
Expression of Target Genes for the Enhancer