About Enhancer
| Enhancer ID: | E_02269 |
| Species: | Mus musculus |
| Position : | chr18:61108475-61108975   |
| Year: | 2019 |
| Title: | Deletion of a Csf1r enhancer selectively impacts CSF1R expression and development of tissue macrophage populations. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 31324781 |
| Tissue: | skin of body |
| Tissue Ontology ID: | UBERON:0002097 |
| Cell Source: | Csf1r enhancer-deletion mouse |
| Cell Type: | macrophage |
| Cell Ontology ID: | CL:0000235 |
| Experiment Type: | Canonical Csf1r FIRE enhancer; current mm10 interval standardized to chr18:61108475-61108975; in vivo FIRE deletion phenotype; Endogenous enhancer perturbation; In vivo functional validation |
| High Throughput Method: | RNA-seq and macrophage population profiling |
| Low Throughput Method: | Enhancer genome editing mouse; flow cytometry; immunohistochemistry; expression analysis; Mouse genetic deletion/knock-in |
About Target Gene
| Target gene : | Csf1r |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Expression of Target Genes for the Enhancer