Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02265
Species: Mus musculus
Position : chr10:177510950-177511040
Year: 2015
Title: A highly conserved NF-百B-responsive enhancer is critical for thymic expression of Aire in mice.
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
PMID:  26364592
Tissue: thymus
Tissue Ontology ID: UBERON:0002370
Cell Source: mTEC
Cell Type: medullary thymic epithelial cell
Cell Ontology ID: CL:0002365
Experiment Type: Enhancer activity assay; Endogenous enhancer perturbation; In vivo functional validation
Low Throughput Method: Luciferase Reporter Assay; Mouse genetic deletion/knock-in
About Target Gene
Target gene : Aire
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer