About Enhancer
| Enhancer ID: | E_02238 |
| Species: | Mus musculus |
| Position : | chr13:116322276-116325052   |
| Year: | 2020 |
| Title: | ATAC-Seq Reveals an Isl1 Enhancer That Regulates Sinoatrial Node Development and Function. |
| Genome Build: | mm39 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 33044128 |
| Tissue: | sinoatrial node |
| Tissue Ontology ID: | UBERON:0002351 |
| Cell Source: | FACS-sorted neonatal mouse sinoatrial node pacemaker cells |
| Cell Type: | pacemaker cardiomyocyte |
| Experiment Type: | Enhancer discovery assay; in vivo enhancer activity assay; endogenous enhancer perturbation assay |
| High Throughput Method: | ATAC-seq |
| Low Throughput Method: | Transgenic mouse enhancer reporter assay; CRISPR/Cas9 2762-bp deletion of Rr303/Isl1-deltaISE; zebrafish enhancer reporter assay; RT-qPCR; histology; ECG; telemetry; cardiac electrophysiology |
About Target Gene
| Target gene : | Isl1 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (mm39)
No overlapping enhancers found in mm39 at this locus.
Expression of Target Genes for the Enhancer