About Enhancer
| Enhancer ID: | E_02193 |
| Species: | Mus musculus |
| Position : | chr17:34520000-34525000   |
| Year: | 2025 |
| Title: | Super-Enhancer-Driven HCG20 Promotes Pulmonary Hypertension Through U2AF2 Splicing. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 40433695 |
| Tissue: | lung |
| Tissue Ontology ID: | UBERON:0002048 |
| Cell Source: | Mouse Pulmonary Artery Endothelial Cells |
| Cell Type: | pulmonary artery endothelial cell |
| Cell Ontology ID: | CL:1001568 |
| Experiment Type: | Enhancer activity assay, Functional perturbation assay; Enhancer activity assay; Endogenous enhancer perturbation; Chromatin-state profiling |
| High Throughput Method: | ChIP-seq, RNA-seq; RNA-seq; ChIP-seq |
| Low Throughput Method: | RT-RT-qPCR, Western blot; CRISPR-Cas9 endogenous deletion/editing; Luciferase reporter assay; ChIP-qPCR; ChIP; RT-qPCR; Reporter assay |
About Target Gene
| Target gene : | Hcg20 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer