Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02184
Species: Mus musculus
Position : chr5:115358083-115360083
Year: 2011
Title: Identification of a novel intronic enhancer responsible for the transcriptional regulation of musashi1 in neural stem/progenitor cells.
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
PMID:  21486496
Tissue: brain
Tissue Ontology ID: UBERON:0000955
Cell Source: Embryonic Stem Cell
Experiment Type: Enhancer activity assay; TF-binding/chromatin assay; Chromatin interaction assay; In vivo functional validation
High Throughput Method: ChIP-seq
Low Throughput Method: Luciferase reporter assay; Reporter assay; ChIP-qPCR/ChIP
About Target Gene
Target gene : Msi1
About TF
TF name : Tfap2a
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Tfap2a Caspase Cascade in Apoptosis pid 57
Tfap2a Hs_Corticotropin-releasing_hormone_signaling_pathway_WP2355_90017 wikipathways 41
Tfap2a Hs_Neural_Crest_Differentiation_WP2064_79263 wikipathways 40
Tfap2a Hs_Ectoderm_Differentiation_WP2858_89329 wikipathways 56
Tfap2a Hs_Hypothetical_Craniofacial_Development_Pathway_WP3655_88473 wikipathways 5
Enhancer Associated Network
Overlapping Enhancers (mm10) 1 found
Enhancer ID Position Tissue Cell Disease
E_02183 chr5:115358083-115360083 brain NA NA
Expression of Target Genes for the Enhancer