Comprehensive information about experimentally validated enhancers
| Enhancer ID: | E_02167 |
| Species: | Mus musculus |
| Position : | chr5:75699926-75706926 |
| Year: | 2024 |
| Title: | TAD border deletion at the Kit locus causes tissue-specific ectopic activation of a neighboring gene. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 38806452 |
| Tissue: | zone of skin |
| Tissue Ontology ID: | UBERON:0000014 |
| Cell Source: | Primary Melanocytes (Kit ?30k) |
| Cell Type: | melanocyte |
| Cell Ontology ID: | CL:0000148 |
| Experiment Type: | Chromatin interaction assay, Functional perturbation assay; Endogenous enhancer perturbation; In vivo functional validation |
| High Throughput Method: | Hi-C, RNA-seq, ChIP-seq |
| Low Throughput Method: | CRISPR Knockout, qRT-PCR, Immunohistochemistry; CRISPR-Cas9 endogenous deletion/editing; Mouse genetic deletion/knock-in |
| Target gene : | Kdr |
| TF name : | NA |
| Regulatory State : | Active |
| GeneName | Pathway Name | Source | Gene Number |
|---|
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_02169 | chr5:75699926-75706926 | bone marrow | mast cell | NA |