About Enhancer
| Enhancer ID: | E_02095 |
| Species: | Mus musculus |
| Position : | chr8:28094779-28095609   |
| Year: | 2020 |
| Title: | HOX paralogs selectively convert binding of ubiquitous transcription factors into tissue-specific patterns of enhancer activation. |
| Genome Build: | mm9 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 33315856 |
| Tissue: | pharyngeal arch |
| Tissue Ontology ID: | UBERON:0002539 |
| Cell Source: | NIH 3T3 |
| CVCL ID: | CVCL_0594 |
| Cell Type: | fibroblast |
| Cell Ontology ID: | CL:0000057 |
| Experiment Type: | Enhancer activity assay; TF binding assay; In vivo functional validation |
| High Throughput Method: | Hoxa2 ChIP-seq; Hoxa3 ChIP-seq; PBX ChIP-seq; MEIS ChIP-seq; H3K27ac ChIP-seq |
| Low Throughput Method: | Luciferase Reporter Assay; ChIP-qPCR; In vivo phenotyping |
About Target Gene
| Target gene : | Zfp703 |
About TF
| TF name : | Hoxa3 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Hoxa3 | Activation of anterior HOX genes in hindbrain development during early embryogenesis | reactome | 120 |
Enhancer Associated Network
Expression of Target Genes for the Enhancer