About Enhancer
| Enhancer ID: | E_01_0992 |
| Species: | mouse |
| Position : | chr3:60377473-60379473   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Inflammatory diseases |
| Pubmed ID: | 32054946 |
| Enhancer experiment: | Western blot, transfection, immunofluorescence, luciferase assay |
| Enhancer experiment description: | We previously reported that a nonsteroidal anti_x0002_infammatory drug (NSAID), phenylbutazone, upregulates MBNL1 expression in DM1 mouse model by demethylation of MeR2, an enhancer element in Mbnl1 intron 1. |
About Target gene
| Target gene : | Mbnl1 |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | We previously reported that a nonsteroidal anti_x0002_infammatory drug (NSAID), phenylbutazone, upregulates MBNL1 expression in DM1 mouse model by demethylation of MeR2, an enhancer element in Mbnl1 intron 1. |
About TF
| TF name : | -- |
| TF experiment: | Western blot??????????????? |
| TF experiment description: | We previously reported that a nonsteroidal anti_x0002_infammatory drug (NSAID), phenylbutazone, upregulates MBNL1 expression in DM1 mouse model by demethylation of MeR2, an enhancer element in Mbnl1 intron 1. |
About Function
| Enhancer function : | We previously reported that a nonsteroidal anti_x0002_infammatory drug (NSAID), phenylbutazone, upregulates MBNL1 expression in DM1 mouse model by demethylation of MeR2, an enhancer element in Mbnl1 intron 1. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
We previously reported that a nonsteroidal anti_x0002_infammatory drug (NSAID), phenylbutazone, upregulates MBNL1 expression in DM1 mouse model by demethylation of MeR2, an enhancer element in Mbnl1 intron 1. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene