About Enhancer
| Enhancer ID: | E_01_0990 |
| Species: | human |
| Position : | chr10:58382379-58384379   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Tumour |
| Pubmed ID: | 32093281 |
| Enhancer experiment: | Transfection, Western blot, immunofluorescence, RT-qPCR, |
| Enhancer experiment description: | Besides, downregulation of PISD with siRNA reduced the level of LC3-II, indicating that depletion of TFAM retarded autophagy via inhibiting PISD expression. |
About Target gene
| Target gene : | -- |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Besides, downregulation of PISD with siRNA reduced the level of LC3-II, indicating that depletion of TFAM retarded autophagy via inhibiting PISD expression. |
About TF
| TF name : | TFAM |
| TF experiment: | ???Western blot??????RT-QPCR? |
| TF experiment description: | Besides, downregulation of PISD with siRNA reduced the level of LC3-II, indicating that depletion of TFAM retarded autophagy via inhibiting PISD expression. |
About Function
| Enhancer function : | Besides, downregulation of PISD with siRNA reduced the level of LC3-II, indicating that depletion of TFAM retarded autophagy via inhibiting PISD expression. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Besides, downregulation of PISD with siRNA reduced the level of LC3-II, indicating that depletion of TFAM retarded autophagy via inhibiting PISD expression. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| TFAM | Transcriptional activation of mitochondrial biogenesis | reactome | 43 |
| TFAM | Huntington's disease | kegg | 182 |
| TFAM | Hs_Mitochondrial_Gene_Expression_WP391_71373 | wikipathways | 11 |
| TFAM | Hs_NAD_metabolism,_sirtuins_and_aging_WP3630_88178 | wikipathways | 8 |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene