About Enhancer
| Enhancer ID: | E_01_0977 |
| Species: | human |
| Position : | chr21:34785474-34787474   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Inflammatory diseases |
| Pubmed ID: | 32209656 |
| Enhancer experiment: | RT qPCR, Western blot, ELISA |
| Enhancer experiment description: | involving the formation of a transcriptional enhancer complex consisting of proto-oncogene c-Jun (c-Jun), RELA proto_x0002_oncogene NF-?B subunit (RelA), RUNX family transcription factor 1 (RUNX1), a |
About Target gene
| Target gene : | -- |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | involving the formation of a transcriptional enhancer complex consisting of proto-oncogene c-Jun (c-Jun), RELA proto_x0002_oncogene NF-?B subunit (RelA), RUNX family transcription factor 1 (RUNX1), a |
About TF
| TF name : | RUNX1(AML1,AML1-EVI-1,AMLCR1,CBF2alpha,CBFA2,EVI-1,PEBP2aB,PEBP2alpha) |
| TF experiment: | RT-qPCR,western blot??????? |
| TF experiment description: | involving the formation of a transcriptional enhancer complex consisting of proto-oncogene c-Jun (c-Jun), RELA proto_x0002_oncogene NF-?B subunit (RelA), RUNX family transcription factor 1 (RUNX1), a |
About Function
| Enhancer function : | involving the formation of a transcriptional enhancer complex consisting of proto-oncogene c-Jun (c-Jun), RELA proto_x0002_oncogene NF-?B subunit (RelA), RUNX family transcription factor 1 (RUNX1), a |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
involving the formation of a transcriptional enhancer complex consisting of proto-oncogene c-Jun (c-Jun), RELA proto_x0002_oncogene NF-?B subunit (RelA), RUNX family transcription factor 1 (RUNX1), a |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| RUNX1 | AndrogenReceptor | netpath | 167 |
| RUNX1 | Organic cation transport | reactome | 9 |
| RUNX1 | RANKL | netpath | 84 |
| RUNX1 | Regulation of nuclear SMAD2/3 signaling | pid | 82 |
| RUNX1 | TGF_beta_Receptor | netpath | 220 |
| RUNX1 | Validated transcriptional targets of deltaNp63 isoforms | pid | 47 |
| RUNX1 | Pathways in cancer | kegg | 321 |
| RUNX1 | Chronic myeloid leukemia | kegg | 69 |
| RUNX1 | Acute myeloid leukemia | kegg | 53 |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene