About Enhancer
| Enhancer ID: |
E_01_0974 |
| Species: |
human |
| Position :
|
chr19:15232997-15234997  |
| Biosample name: |
|
| Experiment class :
|
High+Lowthroughput |
| Enhancer type: |
Enhancer |
| Disease: |
Prostatic cancer |
| Pubmed ID: |
32199616
|
| Enhancer experiment: |
Transfection, migration invasion assay, RT qPCR |
| Enhancer experiment description: |
Bromodomain and extra terminal domain (BET) protein BRD4 binds to super-enhancers (SEs) that drive high expression of oncogenes in many cancers. |
About Target gene
| Target gene : |
-- |
| Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: |
RNA-Seq |
| Target gene experiment description: |
Bromodomain and extra terminal domain (BET) protein BRD4 binds to super-enhancers (SEs) that drive high expression of oncogenes in many cancers. |
About TF
| TF name : |
BRD4(CAP,HUNK1,HUNKI,MCAP) |
| TF experiment: |
??????????RT-qPCR |
| TF experiment description: |
Bromodomain and extra terminal domain (BET) protein BRD4 binds to super-enhancers (SEs) that drive high expression of oncogenes in many cancers. |
About Function
| Enhancer function : |
Bromodomain and extra terminal domain (BET) protein BRD4 binds to super-enhancers (SEs) that drive high expression of oncogenes in many cancers. |
| Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function experiment description: |
Bromodomain and extra terminal domain (BET) protein BRD4 binds to super-enhancers (SEs) that drive high expression of oncogenes in many cancers. |
About SNP
Upstream Pathway Annotation of TF
| GeneName |
Pathway Name |
Source |
Gene Number |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs