About Enhancer
| Enhancer ID: |
E_01_0971 |
| Species: |
human |
| Position :
|
chr22:42123656-42125656
  |
| Biosample name: |
|
| Experiment class :
|
High+Lowthroughput |
| Enhancer type: |
Enhancer |
| Disease: |
-- |
| Pubmed ID: |
33043448
|
| Enhancer experiment: |
pcr,Western blotting |
| Enhancer experiment description: |
The rs5758550A>G SNP apparently turns the region into an enhancer that interacts with the CYP2D6 promoter and increases transcription. |
About Target gene
| Target gene : |
CYP2D6(CPD6,CYP2D,CYP2D7AP,CYP2D7BP,CYP2D7P2,CYP2D8P2,CYP2DL1,CYPIID6,P450-DB1,P450C2D,P450DB1) |
| Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: |
RNA-Seq |
| Target gene experiment description: |
The rs5758550A>G SNP apparently turns the region into an enhancer that interacts with the CYP2D6 promoter and increases transcription. |
About TF
| TF name : |
-- |
| TF experiment: |
pcr,Western blotting |
| TF experiment description: |
The rs5758550A>G SNP apparently turns the region into an enhancer that interacts with the CYP2D6 promoter and increases transcription. |
About Function
| Enhancer function : |
The rs5758550A>G SNP apparently turns the region into an enhancer that interacts with the CYP2D6 promoter and increases transcription. |
| Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function
experiment description: |
The rs5758550A>G SNP apparently turns the region into an enhancer that interacts with the CYP2D6 promoter and increases transcription. |
About SNP
Upstream Pathway Annotation of TF
| GeneName |
Pathway Name |
Source |
Gene Number |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs