About Enhancer
| Enhancer ID: | E_01_0966 |
| Species: | human |
| Position : | chr13:27917232-27919232   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Insulinoma |
| Pubmed ID: | 33060578 |
| Enhancer experiment: | PCR |
| Enhancer experiment description: | NFaT transcription factors, rather than the cano_x005f_x0002_nical PDX1 enhancer complex, are predicted to drive INS transactivation. |
About Target gene
| Target gene : | -- |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | NFaT transcription factors, rather than the cano_x005f_x0002_nical PDX1 enhancer complex, are predicted to drive INS transactivation. |
About TF
| TF name : | PDX1(GSF,IDX-1,IPF1,IUF1,MODY4,PAGEN1,PDX-1,STF-1) |
| TF experiment: | PCR |
| TF experiment description: | NFaT transcription factors, rather than the cano_x005f_x0002_nical PDX1 enhancer complex, are predicted to drive INS transactivation. |
About Function
| Enhancer function : | NFaT transcription factors, rather than the cano_x005f_x0002_nical PDX1 enhancer complex, are predicted to drive INS transactivation. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
NFaT transcription factors, rather than the cano_x005f_x0002_nical PDX1 enhancer complex, are predicted to drive INS transactivation. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| PDX1 | FOXA2 and FOXA3 transcription factor networks | pid | 45 |
| PDX1 | Regulation of gene expression in beta cells | reactome | 17 |
| PDX1 | Regulation of gene expression in early pancreatic precursor cells | reactome | 8 |
| PDX1 | Type II diabetes mellitus | kegg | 44 |
| PDX1 | Maturity onset diabetes of the young | kegg | 25 |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene