About Enhancer
| Enhancer ID: | E_01_0953 |
| Species: | human |
| Position : | chr3:138941350-138943350   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Granulosa cell tumors |
| Pubmed ID: | 32641411 |
| Enhancer experiment: | ChIP-seq?RNA-seq |
| Enhancer experiment description: | This binding induced an enhancer-like chromatin state, leading to transcription of nearby genes, many of which are characteristic of epithelial-to_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x0002_mesenchymal transition. FOXL2C134W also bound hybrid loci in primary AGCT. |
About Target gene
| Target gene : | -- |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | This binding induced an enhancer-like chromatin state, leading to transcription of nearby genes, many of which are characteristic of epithelial-to_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x0002_mesenchymal transition. FOXL2C134W also bound hybrid loci in primary AGCT. |
About TF
| TF name : | FOXL2 |
| TF experiment: | ChIP-seq?RNA-seq |
| TF experiment description: | This binding induced an enhancer-like chromatin state, leading to transcription of nearby genes, many of which are characteristic of epithelial-to_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x0002_mesenchymal transition. FOXL2C134W also bound hybrid loci in primary AGCT. |
About Function
| Enhancer function : | This binding induced an enhancer-like chromatin state, leading to transcription of nearby genes, many of which are characteristic of epithelial-to_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x0002_mesenchymal transition. FOXL2C134W also bound hybrid loci in primary AGCT. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
This binding induced an enhancer-like chromatin state, leading to transcription of nearby genes, many of which are characteristic of epithelial-to_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x0002_mesenchymal transition. FOXL2C134W also bound hybrid loci in primary AGCT. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene