About Enhancer
| Enhancer ID: |
E_01_0945 |
| Species: |
human |
| Position :
|
chr4:38661436-38663436
  |
| Biosample name: |
|
| Experiment class :
|
High+Lowthroughput |
| Enhancer type: |
Enhancer |
| Disease: |
Skin diseases |
| Pubmed ID: |
32659720
|
| Enhancer experiment: |
RT-qPCR,Western blot |
| Enhancer experiment description: |
Over half of KLF3s genomic binding sites occur at active enhancers.KLF3 binds to active enhancers proximal to differentiation genes that are depen_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x0002_dent upon KLF3 for expression. |
About Target gene
| Target gene : |
-- |
| Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: |
RNA-Seq |
| Target gene experiment description: |
Over half of KLF3s genomic binding sites occur at active enhancers.KLF3 binds to active enhancers proximal to differentiation genes that are depen_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x0002_dent upon KLF3 for expression. |
About TF
| TF name : |
KLF3 |
| TF experiment: |
RT-qPCR,Western blot |
| TF experiment description: |
Over half of KLF3s genomic binding sites occur at active enhancers.KLF3 binds to active enhancers proximal to differentiation genes that are depen_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x0002_dent upon KLF3 for expression. |
About Function
| Enhancer function : |
Over half of KLF3s genomic binding sites occur at active enhancers.KLF3 binds to active enhancers proximal to differentiation genes that are depen_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x0002_dent upon KLF3 for expression. |
| Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function
experiment description: |
Over half of KLF3s genomic binding sites occur at active enhancers.KLF3 binds to active enhancers proximal to differentiation genes that are depen_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x0002_dent upon KLF3 for expression. |
About SNP
Upstream Pathway Annotation of TF
| GeneName |
Pathway Name |
Source |
Gene Number |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs