About Enhancer
| Enhancer ID: |
E_01_0940 |
| Species: |
human |
| Position :
|
chr1:153658780-153660780
  |
| Biosample name: |
|
| Experiment class :
|
High+Lowthroughput |
| Enhancer type: |
Enhancer |
| Disease: |
Myocarditis |
| Pubmed ID: |
32668391
|
| Enhancer experiment: |
qRT-PCR?western blot |
| Enhancer experiment description: |
We found that AK085865 specifically in_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x0002_teracts with interleukin enhancer-binding factor 2 (ILF2) and facilitates M2 macrophage polarization by functioning as a negative regulator in the ILF2-ILF3 complex-mediated micro_x0002_RNA (miRNA or miR) processing pathway. |
About Target gene
| Target gene : |
ILF2 |
| Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: |
RNA-Seq |
| Target gene experiment description: |
We found that AK085865 specifically in_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x0002_teracts with interleukin enhancer-binding factor 2 (ILF2) and facilitates M2 macrophage polarization by functioning as a negative regulator in the ILF2-ILF3 complex-mediated micro_x0002_RNA (miRNA or miR) processing pathway. |
About TF
| TF name : |
-- |
| TF experiment: |
qRT-PCR?western blot |
| TF experiment description: |
We found that AK085865 specifically in_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x0002_teracts with interleukin enhancer-binding factor 2 (ILF2) and facilitates M2 macrophage polarization by functioning as a negative regulator in the ILF2-ILF3 complex-mediated micro_x0002_RNA (miRNA or miR) processing pathway. |
About Function
| Enhancer function : |
We found that AK085865 specifically in_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x0002_teracts with interleukin enhancer-binding factor 2 (ILF2) and facilitates M2 macrophage polarization by functioning as a negative regulator in the ILF2-ILF3 complex-mediated micro_x0002_RNA (miRNA or miR) processing pathway. |
| Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function
experiment description: |
We found that AK085865 specifically in_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x005f_x0002_teracts with interleukin enhancer-binding factor 2 (ILF2) and facilitates M2 macrophage polarization by functioning as a negative regulator in the ILF2-ILF3 complex-mediated micro_x0002_RNA (miRNA or miR) processing pathway. |
About SNP
Upstream Pathway Annotation of TF
| GeneName |
Pathway Name |
Source |
Gene Number |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs