About Enhancer
| Enhancer ID: | E_01_0937 |
| Species: | human |
| Position : | chr5:143275121-143277121   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | -- |
| Pubmed ID: | 32673938 |
| Enhancer experiment: | PCR |
| Enhancer experiment description: | DNA methylation standards (100 %; 75 %; 50 %; 25 % and 0 %) and DNA of a female and male donor were bisulfite treated in three independent trials and were used to generate sequencing libraries for 42 CpGs from the NR3C1 1 F promoter region, 84 CpGs of the SLC6A4 5? regulatory region, 5 CpGs located in FKBP5 intron 7, andadditional 12 CpGs located in a potential enhancer element in intron 3 of the OXTR. |
About Target gene
| Target gene : | FKBP5 |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | DNA methylation standards (100 %; 75 %; 50 %; 25 % and 0 %) and DNA of a female and male donor were bisulfite treated in three independent trials and were used to generate sequencing libraries for 42 CpGs from the NR3C1 1 F promoter region, 84 CpGs of the SLC6A4 5? regulatory region, 5 CpGs located in FKBP5 intron 7, andadditional 12 CpGs located in a potential enhancer element in intron 3 of the OXTR.;DNA methylation standards (100 %; 75 %; 50 %; 25 % and 0 %) and DNA of a female and male donor were bisulfite treated in three independent trials and were used to generate sequencing libraries for 42 CpGs from the NR3C1 1 F promoter region, 84 CpGs of the SLC6A4 5? regulatory region, 5 CpGs located in FKBP5 intron 7, andadditional 12 CpGs located in a potential enhancer element in intron 3 of the OXTR. |
About TF
| TF name : | NR3C1(GCCR,GCR,GCRST,GR,GRL) |
| TF experiment: | PCR |
| TF experiment description: | DNA methylation standards (100 %; 75 %; 50 %; 25 % and 0 %) and DNA of a female and male donor were bisulfite treated in three independent trials and were used to generate sequencing libraries for 42 CpGs from the NR3C1 1 F promoter region, 84 CpGs of the SLC6A4 5? regulatory region, 5 CpGs located in FKBP5 intron 7, andadditional 12 CpGs located in a potential enhancer element in intron 3 of the OXTR.;DNA methylation standards (100 %; 75 %; 50 %; 25 % and 0 %) and DNA of a female and male donor were bisulfite treated in three independent trials and were used to generate sequencing libraries for 42 CpGs from the NR3C1 1 F promoter region, 84 CpGs of the SLC6A4 5? regulatory region, 5 CpGs located in FKBP5 intron 7, andadditional 12 CpGs located in a potential enhancer element in intron 3 of the OXTR. |
About Function
| Enhancer function : | DNA methylation standards (100 %; 75 %; 50 %; 25 % and 0 %) and DNA of a female and male donor were bisulfite treated in three independent trials and were used to generate sequencing libraries for 42 CpGs from the NR3C1 1 F promoter region, 84 CpGs of the SLC6A4 5? regulatory region, 5 CpGs located in FKBP5 intron 7, andadditional 12 CpGs located in a potential enhancer element in intron 3 of the OXTR. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
DNA methylation standards (100 %; 75 %; 50 %; 25 % and 0 %) and DNA of a female and male donor were bisulfite treated in three independent trials and were used to generate sequencing libraries for 42 CpGs from the NR3C1 1 F promoter region, 84 CpGs of the SLC6A4 5? regulatory region, 5 CpGs located in FKBP5 intron 7, andadditional 12 CpGs located in a potential enhancer element in intron 3 of the OXTR. |
About SNP
| SNP ID: | rs114435510,rs75975944,rs7636061 |
Upstream Pathway Annotation of TF
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene