About Enhancer
| Enhancer ID: | E_01_0888 |
| Species: | human |
| Position : | chr16:67559754-67561754   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Cancer (cancer) |
| Pubmed ID: | 31451355 |
| Enhancer experiment: | Western blot, PCR, gel electrophoresis |
| Enhancer experiment description: | CCCTC-binding factor (CTCF), cohesion (SMC1), and mediator (MED12) are the top three factors that have been reported as both essential for cellular functions and correlated with a specific looping interaction using chromosome conformation capture (3C) technology. |
About Target gene
| Target gene : | -- |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | CCCTC-binding factor (CTCF), cohesion (SMC1), and mediator (MED12) are the top three factors that have been reported as both essential for cellular functions and correlated with a specific looping interaction using chromosome conformation capture (3C) technology. |
About TF
| TF name : | CTCF(MRD21) |
| TF experiment: | Western blot,PCR,???? |
| TF experiment description: | CCCTC-binding factor (CTCF), cohesion (SMC1), and mediator (MED12) are the top three factors that have been reported as both essential for cellular functions and correlated with a specific looping interaction using chromosome conformation capture (3C) technology. |
About Function
| Enhancer function : | CCCTC-binding factor (CTCF), cohesion (SMC1), and mediator (MED12) are the top three factors that have been reported as both essential for cellular functions and correlated with a specific looping interaction using chromosome conformation capture (3C) technology. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
CCCTC-binding factor (CTCF), cohesion (SMC1), and mediator (MED12) are the top three factors that have been reported as both essential for cellular functions and correlated with a specific looping interaction using chromosome conformation capture (3C) technology. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| CTCF | Activation of anterior HOX genes in hindbrain development during early embryogenesis | reactome | 120 |
| CTCF | TGF_beta_Receptor | netpath | 220 |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene