ENdb-Search-Detail

About Enhancer

Enhancer ID:	E_01_0810
Species:	human
Position :	chrX:67541163-67543163
Biosample name:
Experiment class :	High+Lowthroughput
Enhancer type:	Enhancer
Disease:	Bladder cancer (bca)
Pubmed ID:	29964053
Enhancer experiment:	Real time quantitative PCR, flow cytometry, statistical analysis
Enhancer experiment description:	Specifically, eRNA MARC1 (eMARC1), transcribed from androgen receptor (AR) activated enhancer that was responsible for activation of nearby coding transcription units [20, 21], was identified as an androgen associated AR-activated eRNA [22].

Target gene :	--
Strong evidence:	qRT-PCR,qPCR,ChIP,3C
Less strong evidence:	RNA-Seq
Target gene experiment description:	Specifically, eRNA MARC1 (eMARC1), transcribed from androgen receptor (AR) activated enhancer that was responsible for activation of nearby coding transcription units [20, 21], was identified as an androgen associated AR-activated eRNA [22].

TF name :	AR(AIS8,DHTR,HUMARA,HYSP1,KD,NR3C4,SBMA,SMAX1,TFM,AR)
TF experiment:	Real-time quantitative PCR,?????,????
TF experiment description:	Specifically, eRNA MARC1 (eMARC1), transcribed from androgen receptor (AR) activated enhancer that was responsible for activation of nearby coding transcription units [20, 21], was identified as an androgen associated AR-activated eRNA [22].

Enhancer function :	Specifically, eRNA MARC1 (eMARC1), transcribed from androgen receptor (AR) activated enhancer that was responsible for activation of nearby coding transcription units [20, 21], was identified as an androgen associated AR-activated eRNA [22].
Enhancer function experiment:	Immunohistochemical staining
Enhancer function experiment description:	Specifically, eRNA MARC1 (eMARC1), transcribed from androgen receptor (AR) activated enhancer that was responsible for activation of nearby coding transcription units [20, 21], was identified as an androgen associated AR-activated eRNA [22].

SNP ID:

GeneName	Pathway Name	Source	Gene Number
AR	Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3	reactome	65
AR	Alpha6Beta4Integrin	netpath	74
AR	AndrogenReceptor	netpath	167
AR	Coregulation of Androgen receptor activity	pid	61
AR	FOXA1 transcription factor network	pid	45
AR	IL6	netpath	85
AR	Nongenotropic Androgen signaling	pid	31
AR	Notch-mediated HES/HEY network	pid	48
AR	Nuclear Receptor transcription pathway	reactome	51
AR	Regulation of Androgen receptor activity	pid	54
AR	Regulation of nuclear beta catenin signaling and target gene transcription	pid	80
AR	Regulation of nuclear SMAD2/3 signaling	pid	82
AR	TGF_beta_Receptor	netpath	220
AR	Oocyte meiosis	kegg	110
AR	Pathways in cancer	kegg	321
AR	Prostate cancer	kegg	85
AR	Hs_DNA_Damage_Response_WP707_82937	wikipathways	28
AR	Hs_miRNA_Regulation_of_DNA_Damage_Response_WP1530_84694	wikipathways	28
AR	Hs_Integrated_Breast_Cancer_Pathway_WP1984_82941	wikipathways	122
AR	Hs_Sudden_Infant_Death_Syndrome_(SIDS)_Susceptibility_Pathways_WP706_86078	wikipathways	33
AR	Hs_Androgen_receptor_signaling_pathway_WP138_79958	wikipathways	27

The number on yellow line represents the distance between enhancer and target gene