About Enhancer
| Enhancer ID: | E_01_0781 |
| Species: | human |
| Position : | chr1:207031208-207033208   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Obesity, diabetes |
| Pubmed ID: | 30072891 |
| Enhancer experiment: | Real time PCR, immunofluorescence staining |
| Enhancer experiment description: | In addition, the mRNA expression levels of peroxisome proliferators-activated receptor ?/? (PPAR?/?), CCAAT/enhancer binding protein? (C/EBP?), Nuclear respiratory factor 1/2 (NRF1/2), Uncoupling protein 2 (UCP2), and phosphofructokinase 2/fructose-2, 6-bisphosphatase 2 (PFKFB2) were detected by RT-PCR. |
About Target gene
| Target gene : | PFKFB2 |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | In addition, the mRNA expression levels of peroxisome proliferators-activated receptor ?/? (PPAR?/?), CCAAT/enhancer binding protein? (C/EBP?), Nuclear respiratory factor 1/2 (NRF1/2), Uncoupling protein 2 (UCP2), and phosphofructokinase 2/fructose-2, 6-bisphosphatase 2 (PFKFB2) were detected by RT-PCR. |
About TF
| TF name : | -- |
| TF experiment: | real-time PCR,?????? |
| TF experiment description: | In addition, the mRNA expression levels of peroxisome proliferators-activated receptor ?/? (PPAR?/?), CCAAT/enhancer binding protein? (C/EBP?), Nuclear respiratory factor 1/2 (NRF1/2), Uncoupling protein 2 (UCP2), and phosphofructokinase 2/fructose-2, 6-bisphosphatase 2 (PFKFB2) were detected by RT-PCR. |
About Function
| Enhancer function : | In addition, the mRNA expression levels of peroxisome proliferators-activated receptor ?/? (PPAR?/?), CCAAT/enhancer binding protein? (C/EBP?), Nuclear respiratory factor 1/2 (NRF1/2), Uncoupling protein 2 (UCP2), and phosphofructokinase 2/fructose-2, 6-bisphosphatase 2 (PFKFB2) were detected by RT-PCR. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
In addition, the mRNA expression levels of peroxisome proliferators-activated receptor ?/? (PPAR?/?), CCAAT/enhancer binding protein? (C/EBP?), Nuclear respiratory factor 1/2 (NRF1/2), Uncoupling protein 2 (UCP2), and phosphofructokinase 2/fructose-2, 6-bisphosphatase 2 (PFKFB2) were detected by RT-PCR. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene