About Enhancer
| Enhancer ID: | E_01_0765 |
| Species: | human |
| Position : | chr1:150923029-150925029   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Intellectual disability |
| Pubmed ID: | 30103804 |
| Enhancer experiment: | RT-PCR, Weston blot, immunofluorescence staining, chip SEQ, RNA SEQ, statistical analysis |
| Enhancer experiment description: | Results Here, we show that loss of SETDB1 does not result in large-scale H3K9me3 changes at the Xi, but unexpectedly we observed striking decompaction of the Xi territory. |
About Target gene
| Target gene : | SETDB1(AU022152,ESET,KMT1E,mKIAA0067) |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Results Here, we show that loss of SETDB1 does not result in large-scale H3K9me3 changes at the Xi, but unexpectedly we observed striking decompaction of the Xi territory. |
About TF
| TF name : | -- |
| TF experiment: | RT-PCR,weston blot,??????,ChIP-Seq,RNA-Seq,???? |
| TF experiment description: | Results Here, we show that loss of SETDB1 does not result in large-scale H3K9me3 changes at the Xi, but unexpectedly we observed striking decompaction of the Xi territory. |
About Function
| Enhancer function : | Results Here, we show that loss of SETDB1 does not result in large-scale H3K9me3 changes at the Xi, but unexpectedly we observed striking decompaction of the Xi territory. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Results Here, we show that loss of SETDB1 does not result in large-scale H3K9me3 changes at the Xi, but unexpectedly we observed striking decompaction of the Xi territory. |
About SNP
| SNP ID: | rs140261831,rs113985890,rs190632360,rs144991617 |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene