About Enhancer
| Enhancer ID: | E_01_0745 |
| Species: | human |
| Position : | chr16:67559736-67561736   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | -- |
| Pubmed ID: | 30150754 |
| Enhancer experiment: | ATAC-seq,PCR,3D fluorescence in situ hybridization (FISH) |
| Enhancer experiment description: | Examination of chromatin interaction around functional elements such as promoters and CTCF binding sites within 2000 bp regions at a 10-bp resolution revealed a clear pattern of separation of interaction domains anchored at promoters of actively transcribed genes and at CTCF binding sites (Fig. 2c). |
About Target gene
| Target gene : | -- |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Examination of chromatin interaction around functional elements such as promoters and CTCF binding sites within 2000 bp regions at a 10-bp resolution revealed a clear pattern of separation of interaction domains anchored at promoters of actively transcribed genes and at CTCF binding sites (Fig. 2c). |
About TF
| TF name : | CTCF(MRD21) |
| TF experiment: | ATAC-seq,PCR,3D fluorescence in situ hybridization (FISH) |
| TF experiment description: | Examination of chromatin interaction around functional elements such as promoters and CTCF binding sites within 2000 bp regions at a 10-bp resolution revealed a clear pattern of separation of interaction domains anchored at promoters of actively transcribed genes and at CTCF binding sites (Fig. 2c). |
About Function
| Enhancer function : | Examination of chromatin interaction around functional elements such as promoters and CTCF binding sites within 2000 bp regions at a 10-bp resolution revealed a clear pattern of separation of interaction domains anchored at promoters of actively transcribed genes and at CTCF binding sites (Fig. 2c). |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Examination of chromatin interaction around functional elements such as promoters and CTCF binding sites within 2000 bp regions at a 10-bp resolution revealed a clear pattern of separation of interaction domains anchored at promoters of actively transcribed genes and at CTCF binding sites (Fig. 2c). |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| CTCF | Activation of anterior HOX genes in hindbrain development during early embryogenesis | reactome | 120 |
| CTCF | TGF_beta_Receptor | netpath | 220 |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene