About Enhancer
| Enhancer ID: | E_01_0699 |
| Species: | human |
| Position : | chr17:42697888-42699888   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Nothing |
| Pubmed ID: | 30228822 |
| Enhancer experiment: | Hematoxylin-Eosin Staining,Alizarin Red Staining and Alkaline Phosphatase Staining,Western Blotting,Protein Extraction,Reverse Transcription and Quantitative PCR |
| Enhancer experiment description: | In the present study, our group discovered that a histone methyltransferase enhancer of zeste1 (EZH1) was drastically downregulated in Thp1 cells stimulated by TCP, indicating that EZH1 may participate in the macrophage phenotype shifting. |
About Target gene
| Target gene : | EZH1 |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | In the present study, our group discovered that a histone methyltransferase enhancer of zeste1 (EZH1) was drastically downregulated in Thp1 cells stimulated by TCP, indicating that EZH1 may participate in the macrophage phenotype shifting. |
About TF
| TF name : | -- |
| TF experiment: | Hematoxylin-Eosin Staining,Alizarin Red Staining and Alkaline Phosphatase Staining,Western Blotting,Protein Extraction,Reverse Transcription and Quantitative PCR |
| TF experiment description: | In the present study, our group discovered that a histone methyltransferase enhancer of zeste1 (EZH1) was drastically downregulated in Thp1 cells stimulated by TCP, indicating that EZH1 may participate in the macrophage phenotype shifting. |
About Function
| Enhancer function : | In the present study, our group discovered that a histone methyltransferase enhancer of zeste1 (EZH1) was drastically downregulated in Thp1 cells stimulated by TCP, indicating that EZH1 may participate in the macrophage phenotype shifting. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
In the present study, our group discovered that a histone methyltransferase enhancer of zeste1 (EZH1) was drastically downregulated in Thp1 cells stimulated by TCP, indicating that EZH1 may participate in the macrophage phenotype shifting. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene