About Enhancer
| Enhancer ID: | E_01_0697 |
| Species: | human |
| Position : | chr16:69704597-69706597   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Diabetes, inflammation, cancer |
| Pubmed ID: | 30250574 |
| Enhancer experiment: | RT?qPCR,Western blot,Cell viability assay,Immunofluorescence assay,Flow cytometric analysis |
| Enhancer experiment description: | STE unregulated phosphorylated p53, NF ?B p65, Nrf2, HO 1, and NQO1 expression levels in the hOMF cells. The present study demonstrated that STE appears to promote oral disease. |
About Target gene
| Target gene : | NQO1 |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | STE unregulated phosphorylated p53, NF ?B p65, Nrf2, HO 1, and NQO1 expression levels in the hOMF cells. The present study demonstrated that STE appears to promote oral disease. |
About TF
| TF name : | -- |
| TF experiment: | RT?qPCR,Western blot,Cell viability assay,Immunofluorescence assay,Flow cytometric analysis |
| TF experiment description: | STE unregulated phosphorylated p53, NF ?B p65, Nrf2, HO 1, and NQO1 expression levels in the hOMF cells. The present study demonstrated that STE appears to promote oral disease. |
About Function
| Enhancer function : | STE unregulated phosphorylated p53, NF ?B p65, Nrf2, HO 1, and NQO1 expression levels in the hOMF cells. The present study demonstrated that STE appears to promote oral disease. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
STE unregulated phosphorylated p53, NF ?B p65, Nrf2, HO 1, and NQO1 expression levels in the hOMF cells. The present study demonstrated that STE appears to promote oral disease. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene