About Enhancer
| Enhancer ID: | E_01_0695 |
| Species: | human |
| Position : | chr16:55386943-55388943   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Lung cancer |
| Pubmed ID: | 30256540 |
| Enhancer experiment: | qRT-PCR,Immunofluorescence,Western blot,Wound healing assay,Transwell assays,Luciferase assay,Immunohistochemistry and in situ hybridization |
| Enhancer experiment description: | These results suggested that exosomal lnc-MMP2-2 might regulate the migration and invasion of lung cancer cells into the vasculature by promoting MMP2 expression, suggesting this lncRNA as a novel therapeutic target and predictive marker of tumor metastasis in lung cancer |
About Target gene
| Target gene : | -- |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | These results suggested that exosomal lnc-MMP2-2 might regulate the migration and invasion of lung cancer cells into the vasculature by promoting MMP2 expression, suggesting this lncRNA as a novel therapeutic target and predictive marker of tumor metastasis in lung cancer |
About TF
| TF name : | MMP2 |
| TF experiment: | qRT-PCR,Immunofluorescence,Western blot,Wound healing assay,Transwell assays,Luciferase assay,Immunohistochemistry and in situ hybridization |
| TF experiment description: | These results suggested that exosomal lnc-MMP2-2 might regulate the migration and invasion of lung cancer cells into the vasculature by promoting MMP2 expression, suggesting this lncRNA as a novel therapeutic target and predictive marker of tumor metastasis in lung cancer |
About Function
| Enhancer function : | These results suggested that exosomal lnc-MMP2-2 might regulate the migration and invasion of lung cancer cells into the vasculature by promoting MMP2 expression, suggesting this lncRNA as a novel therapeutic target and predictive marker of tumor metastasis in lung cancer |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
These results suggested that exosomal lnc-MMP2-2 might regulate the migration and invasion of lung cancer cells into the vasculature by promoting MMP2 expression, suggesting this lncRNA as a novel therapeutic target and predictive marker of tumor metastasis in lung cancer |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene