About Enhancer
| Enhancer ID: | E_01_0690 |
| Species: | human |
| Position : | chr7:27159901-27161901   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Leukemia |
| Pubmed ID: | 30270123 |
| Enhancer experiment: | Flow Cytometry,Cell Proliferation and Colony Formation Assays,Immunoprecipitation,4C-seq Analysis,ChIP, ChIP-Seq and Bioinformatics Analyses,Real-time PCR and RNA-seq Analyses,Global Analysis on the Enhancer Landscape |
| Enhancer experiment description: | Therapeutic targeting of HOXA9-dependent enhancer reorganization can be an effective therapeutic strategy in acute leukemia with HOXA9 overexpression. |
About Target gene
| Target gene : | -- |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Therapeutic targeting of HOXA9-dependent enhancer reorganization can be an effective therapeutic strategy in acute leukemia with HOXA9 overexpression. |
About TF
| TF name : | HOXA9(D6a9,Hox-1.7) |
| TF experiment: | Flow Cytometry,Cell Proliferation and Colony Formation Assays,Immunoprecipitation,4C-seq Analysis,ChIP, ChIP-Seq and Bioinformatics Analyses,Real-time PCR and RNA-seq Analyses,Global Analysis on the Enhancer Landscape |
| TF experiment description: | Therapeutic targeting of HOXA9-dependent enhancer reorganization can be an effective therapeutic strategy in acute leukemia with HOXA9 overexpression. |
About Function
| Enhancer function : | Therapeutic targeting of HOXA9-dependent enhancer reorganization can be an effective therapeutic strategy in acute leukemia with HOXA9 overexpression. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Therapeutic targeting of HOXA9-dependent enhancer reorganization can be an effective therapeutic strategy in acute leukemia with HOXA9 overexpression. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| HOXA9 | TGF_beta_Receptor | netpath | 220 |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene