About Enhancer
| Enhancer ID: | E_01_0672 |
| Species: | human |
| Position : | chr8:47734236-47736236   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Hepatocellular carcinoma |
| Pubmed ID: | 30325409 |
| Enhancer experiment: | Lentiviral-shRNA packaging and infectionWestern blot?Quantitative Real-time PCR(qRT-PCR)?Cell proliferation and Colony formation assa?y |
| Enhancer experiment description: | Thus although our results support the notion that CEBPD acts as a tumor suppressor in HCC, its action does not involve impairing compartment expansion per se but more likely acts through improving anti-cancer immunity. |
About Target gene
| Target gene : | -- |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Thus although our results support the notion that CEBPD acts as a tumor suppressor in HCC, its action does not involve impairing compartment expansion per se but more likely acts through improving anti-cancer immunity. |
About TF
| TF name : | CEBPD |
| TF experiment: | Lentiviral-shRNA packaging and infectionWestern blot?Quantitative Real-time PCR(qRT-PCR)?Cell proliferation and Colony formation assa?y |
| TF experiment description: | Thus although our results support the notion that CEBPD acts as a tumor suppressor in HCC, its action does not involve impairing compartment expansion per se but more likely acts through improving anti-cancer immunity. |
About Function
| Enhancer function : | Thus although our results support the notion that CEBPD acts as a tumor suppressor in HCC, its action does not involve impairing compartment expansion per se but more likely acts through improving anti-cancer immunity. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Thus although our results support the notion that CEBPD acts as a tumor suppressor in HCC, its action does not involve impairing compartment expansion per se but more likely acts through improving anti-cancer immunity. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| CEBPD | C-MYB transcription factor network | pid | 87 |
| CEBPD | FOXA2 and FOXA3 transcription factor networks | pid | 45 |
| CEBPD | IL6-mediated signaling events | pid | 48 |
| CEBPD | Regulation of retinoblastoma protein | pid | 67 |
| CEBPD | Transcriptional regulation of white adipocyte differentiation | reactome | 79 |
| CEBPD | Validated targets of C-MYC transcriptional repression | pid | 63 |
| CEBPD | Validated transcriptional targets of deltaNp63 isoforms | pid | 47 |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene