About Enhancer
| Enhancer ID: | E_01_0670 |
| Species: | human |
| Position : | chrX:152895420-152897420   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Epidermal differentiation and squamous cell carcinoma |
| Pubmed ID: | 30337687 |
| Enhancer experiment: | Poorly differentiated, including head and neck, cervical and oesophageal, squamous cell carcinomas display loss of ZNF185 expression. Together, these studies reinforce that p63 is a crucial gene for maintaining epithelial tissue integrity and support the deregulation of the cell-cell adhesion programme,which plays a critical role in carcinoma development. |
| Enhancer experiment description: | -- |
About Target gene
| Target gene : | ZNF185 |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | -- |
About TF
| TF name : | -- |
| TF experiment: | Poorly differentiated, including head and neck, cervical and oesophageal, squamous cell carcinomas display loss of ZNF185 expression. Together, these studies reinforce that p63 is a crucial gene for maintaining epithelial tissue integrity and support the deregulation of the cell-cell adhesion programme,which plays a critical role in carcinoma development. |
| TF experiment description: | -- |
About Function
| Enhancer function : | -- |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
-- |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene