About Enhancer
| Enhancer ID: |
E_01_0658 |
| Species: |
human |
| Position :
|
chrX:72326686-72328686
  |
| Biosample name: |
|
| Experiment class :
|
High+Lowthroughput |
| Enhancer type: |
Enhancer |
| Disease: |
Idiopathic pulmonary fibrosis (ipf) |
| Pubmed ID: |
30358439
|
| Enhancer experiment: |
RNA interference?Immunoblots?Immunoprecipitation?Immunofluorescent staining?Type I collagen gel contraction assay ?qRT-PCR?ChIP-qPCR |
| Enhancer experiment description: |
These data suggest that HDAC8 contributes to pulmonary fibrosis and that there is a therapeutic potential for HDAC8 inhibitors to treat IPF as well as other fibrotic lung diseases |
About Target gene
| Target gene : |
HDAC8 |
| Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: |
RNA-Seq |
| Target gene experiment description: |
These data suggest that HDAC8 contributes to pulmonary fibrosis and that there is a therapeutic potential for HDAC8 inhibitors to treat IPF as well as other fibrotic lung diseases |
About TF
| TF name : |
-- |
| TF experiment: |
RNA interference?Immunoblots?Immunoprecipitation?Immunofluorescent staining?Type I collagen gel contraction assay ?qRT-PCR?ChIP-qPCR |
| TF experiment description: |
These data suggest that HDAC8 contributes to pulmonary fibrosis and that there is a therapeutic potential for HDAC8 inhibitors to treat IPF as well as other fibrotic lung diseases |
About Function
| Enhancer function : |
These data suggest that HDAC8 contributes to pulmonary fibrosis and that there is a therapeutic potential for HDAC8 inhibitors to treat IPF as well as other fibrotic lung diseases |
| Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function
experiment description: |
These data suggest that HDAC8 contributes to pulmonary fibrosis and that there is a therapeutic potential for HDAC8 inhibitors to treat IPF as well as other fibrotic lung diseases |
About SNP
Upstream Pathway Annotation of TF
| GeneName |
Pathway Name |
Source |
Gene Number |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs