About Enhancer
| Enhancer ID: | E_01_0639 |
| Species: | mouse |
| Position : | chr15:61854218-61856218   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Metastatic breast cancer |
| Pubmed ID: | 30419347 |
| Enhancer experiment: | 3 qRT-PCR,Western blot,siRNA knockdowns, Chromatin immunoprecipitation (ChIP),Lentivirus infection,Cell invasion assay,RNAseq |
| Enhancer experiment description: | Myc plays a key role in aggressive proliferation-related phenotypes exhibited by breast cancer cells expressing ER? mutations. |
About Target gene
| Target gene : | Myc(MRTLC,bHLHe39,c-Myc) |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Myc plays a key role in aggressive proliferation-related phenotypes exhibited by breast cancer cells expressing ER? mutations. |
About TF
| TF name : | -- |
| TF experiment: | 3 qRT-PCR,Western blot,siRNA knockdowns, Chromatin immunoprecipitation (ChIP),Lentivirus infection,Cell invasion assay,RNAseq |
| TF experiment description: | Myc plays a key role in aggressive proliferation-related phenotypes exhibited by breast cancer cells expressing ER? mutations. |
About Function
| Enhancer function : | Myc plays a key role in aggressive proliferation-related phenotypes exhibited by breast cancer cells expressing ER? mutations. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Myc plays a key role in aggressive proliferation-related phenotypes exhibited by breast cancer cells expressing ER? mutations. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene