About Enhancer
| Enhancer ID: |
E_01_0603 |
| Species: |
human |
| Position :
|
chr1:247413679-247415679
  |
| Biosample name: |
|
| Experiment class :
|
High+Lowthroughput |
| Enhancer type: |
Enhancer |
| Disease: |
Endometrial inflammasome activation accompanies |
| Pubmed ID: |
32488243
|
| Enhancer experiment: |
Immunohistochemistry?Fluorescent immunohistochemistry?Western immunoblotting |
| Enhancer experiment description: |
Specific involvement of NLRP3 inflammasome activation in IL-1beta and IL-18 release after hormone withdrawal was investigated via application of the NLRP3 inflammasome inhibitor MCC950 at the time of hormone withdrawal. |
About Target gene
| Target gene : |
NLRP3 |
| Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: |
RNA-Seq |
| Target gene experiment description: |
Specific involvement of NLRP3 inflammasome activation in IL-1beta and IL-18 release after hormone withdrawal was investigated via application of the NLRP3 inflammasome inhibitor MCC950 at the time of hormone withdrawal. |
About TF
| TF name : |
-- |
| TF experiment: |
Immunohistochemistry?Fluorescent immunohistochemistry?Western immunoblotting |
| TF experiment description: |
Specific involvement of NLRP3 inflammasome activation in IL-1beta and IL-18 release after hormone withdrawal was investigated via application of the NLRP3 inflammasome inhibitor MCC950 at the time of hormone withdrawal. |
About Function
| Enhancer function : |
Specific involvement of NLRP3 inflammasome activation in IL-1beta and IL-18 release after hormone withdrawal was investigated via application of the NLRP3 inflammasome inhibitor MCC950 at the time of hormone withdrawal. |
| Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function
experiment description: |
Specific involvement of NLRP3 inflammasome activation in IL-1beta and IL-18 release after hormone withdrawal was investigated via application of the NLRP3 inflammasome inhibitor MCC950 at the time of hormone withdrawal. |
About SNP
Upstream Pathway Annotation of TF
| GeneName |
Pathway Name |
Source |
Gene Number |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs