About Enhancer
| Enhancer ID: | E_01_0584 |
| Species: | human |
| Position : | chrX:49247655-49249655   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Autoimmune diseases |
| Pubmed ID: | 32362325 |
| Enhancer experiment: | PBAT-seq, ChIP-seq, ATAC-seq,RNA-seq |
| Enhancer experiment description: | Thus, naive Treg cell-specific CpG hypomethylation had a key role in controlling Treg cell-specific gene transcription and epigenetic modification. |
About Target gene
| Target gene : | -- |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Thus, naive Treg cell-specific CpG hypomethylation had a key role in controlling Treg cell-specific gene transcription and epigenetic modification. |
About TF
| TF name : | FOXP3 |
| TF experiment: | PBAT-seq, ChIP-seq, ATAC-seq,RNA-seq |
| TF experiment description: | Thus, naive Treg cell-specific CpG hypomethylation had a key role in controlling Treg cell-specific gene transcription and epigenetic modification. |
About Function
| Enhancer function : | Thus, naive Treg cell-specific CpG hypomethylation had a key role in controlling Treg cell-specific gene transcription and epigenetic modification. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Thus, naive Treg cell-specific CpG hypomethylation had a key role in controlling Treg cell-specific gene transcription and epigenetic modification. |
About SNP
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| FOXP3 | Calcineurin-regulated NFAT-dependent transcription in lymphocytes | pid | 50 |
| FOXP3 | IL2 signaling events mediated by STAT5 | pid | 30 |
| FOXP3 | Hs_Allograft_Rejection_WP2328_90020 | wikipathways | 12 |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene