About Enhancer
| Enhancer ID: | E_01_0573 |
| Species: | human |
| Position : | chr19:54613960-54615960   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Autoimmune diseases |
| Pubmed ID: | 32321755 |
| Enhancer experiment: | quantitative PCR?ChIP |
| Enhancer experiment description: | This region possesses multiple YY1 sites, and complexes of the promoter/enhancer combination were isolated using anti-YY1 in chromatin immunoprecipitation loop. CRISPR-mediated deletion of the 3-kb region lowers LILRB1 expression in human NKL cells. |
About Target gene
| Target gene : | LILRB1 |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | This region possesses multiple YY1 sites, and complexes of the promoter/enhancer combination were isolated using anti-YY1 in chromatin immunoprecipitation loop. CRISPR-mediated deletion of the 3-kb region lowers LILRB1 expression in human NKL cells. |
About TF
| TF name : | -- |
| TF experiment: | quantitative PCR?ChIP |
| TF experiment description: | This region possesses multiple YY1 sites, and complexes of the promoter/enhancer combination were isolated using anti-YY1 in chromatin immunoprecipitation loop. CRISPR-mediated deletion of the 3-kb region lowers LILRB1 expression in human NKL cells. |
About Function
| Enhancer function : | This region possesses multiple YY1 sites, and complexes of the promoter/enhancer combination were isolated using anti-YY1 in chromatin immunoprecipitation loop. CRISPR-mediated deletion of the 3-kb region lowers LILRB1 expression in human NKL cells. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
This region possesses multiple YY1 sites, and complexes of the promoter/enhancer combination were isolated using anti-YY1 in chromatin immunoprecipitation loop. CRISPR-mediated deletion of the 3-kb region lowers LILRB1 expression in human NKL cells. |
About SNP
| SNP ID: | rs1061679 |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene