About Enhancer
| Enhancer ID: | E_01_0532 |
| Species: | human |
| Position : | chr3:108040485-108042485   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Cancer, melanoma |
| Pubmed ID: | 29707136 |
| Enhancer experiment: | Flow Cytometry,Immunoblotting,ATP assay,In vitro phagocytosis assay,In vivo phagocytosis assay,western blot, |
| Enhancer experiment description: | Thus, normoxic vs. hypoxic and live vs. dying cell contexts influence the ultimate immunomodulatory roles of melanoma cell-associated BNIP3. |
About Target gene
| Target gene : | CALR,BNIP3 |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Thus, normoxic vs. hypoxic and live vs. dying cell contexts influence the ultimate immunomodulatory roles of melanoma cell-associated BNIP3.;Thus, normoxic vs. hypoxic and live vs. dying cell contexts influence the ultimate immunomodulatory roles of melanoma cell-associated BNIP3.;Thus, normoxic vs. hypoxic and live vs. dying cell contexts influence the ultimate immunomodulatory roles of melanoma cell-associated BNIP3. |
About TF
| TF name : | CD47 |
| TF experiment: | Flow Cytometry,Immunoblotting,ATP assay,In vitro phagocytosis assay,In vivo phagocytosis assay,western blot, |
| TF experiment description: | Thus, normoxic vs. hypoxic and live vs. dying cell contexts influence the ultimate immunomodulatory roles of melanoma cell-associated BNIP3.;Thus, normoxic vs. hypoxic and live vs. dying cell contexts influence the ultimate immunomodulatory roles of melanoma cell-associated BNIP3.;Thus, normoxic vs. hypoxic and live vs. dying cell contexts influence the ultimate immunomodulatory roles of melanoma cell-associated BNIP3. |
About Function
| Enhancer function : | Thus, normoxic vs. hypoxic and live vs. dying cell contexts influence the ultimate immunomodulatory roles of melanoma cell-associated BNIP3. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Thus, normoxic vs. hypoxic and live vs. dying cell contexts influence the ultimate immunomodulatory roles of melanoma cell-associated BNIP3. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| CD47 | Beta3 integrin cell surface interactions | pid | 44 |
| CD47 | Cell surface interactions at the vascular wall | reactome | 52 |
| CD47 | Integrin cell surface interactions | reactome | 67 |
| CD47 | Signal regulatory protein (SIRP) family interactions | reactome | 13 |
| CD47 | ECM-receptor interaction | kegg | 84 |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene