About Enhancer
| Enhancer ID: |
E_01_0450 |
| Species: |
human |
| Position :
|
chr12:6784343-6786343
  |
| Biosample name: |
|
| Experiment class :
|
High+Lowthroughput |
| Enhancer type: |
Enhancer |
| Disease: |
Granulomatosis with polyangiitis (gpa) |
| Pubmed ID: |
29799396
|
| Enhancer experiment: |
Flow cytometric analysis,Transcriptome,biological database analysis |
| Enhancer experiment description: |
Employing a combined phenotypic and transcriptomic approach we disclosed a Th1/Th17 phenotype as well as innate and adaptive functions of CD4+CD8+ double-positive T-cells in GPA. |
About Target gene
| Target gene : |
CD4 |
| Strong evidence: |
qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: |
RNA-Seq |
| Target gene experiment description: |
Employing a combined phenotypic and transcriptomic approach we disclosed a Th1/Th17 phenotype as well as innate and adaptive functions of CD4+CD8+ double-positive T-cells in GPA. |
About TF
| TF name : |
-- |
| TF experiment: |
Flow cytometric analysis,Transcriptome,biological database analysis |
| TF experiment description: |
Employing a combined phenotypic and transcriptomic approach we disclosed a Th1/Th17 phenotype as well as innate and adaptive functions of CD4+CD8+ double-positive T-cells in GPA. |
About Function
| Enhancer function : |
Employing a combined phenotypic and transcriptomic approach we disclosed a Th1/Th17 phenotype as well as innate and adaptive functions of CD4+CD8+ double-positive T-cells in GPA. |
| Enhancer function experiment: |
Immunohistochemical staining |
Enhancer function
experiment description: |
Employing a combined phenotypic and transcriptomic approach we disclosed a Th1/Th17 phenotype as well as innate and adaptive functions of CD4+CD8+ double-positive T-cells in GPA. |
About SNP
Upstream Pathway Annotation of TF
| GeneName |
Pathway Name |
Source |
Gene Number |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene
Expression of target genes for the
enhancer
Enhancer associated SNPs