About Enhancer
| Enhancer ID: | E_01_0377 |
| Species: | human |
| Position : | chr4:152317572-152319572   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | -- |
| Pubmed ID: | 31733305 |
| Enhancer experiment: | PCR, gel electrophoresis, gene knockdown, immunofluorescence staining |
| Enhancer experiment description: | FBXW7 promotes pathological cardiac hypertrophy by targeting EZH2-SIX1 signaling. |
About Target gene
| Target gene : | SIX1(BOS3,DFNA23,TIP39) |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | FBXW7 promotes pathological cardiac hypertrophy by targeting EZH2-SIX1 signaling.;FBXW7 promotes pathological cardiac hypertrophy by targeting EZH2-SIX1 signaling.;FBXW7 promotes pathological cardiac hypertrophy by targeting EZH2-SIX1 signaling. |
About TF
| TF name : | FBXW7EZH2(ENX-1,ENX1b,KMT6,KMT6A,WVS,WVS2,EZH2) |
| TF experiment: | PCR????????????????? |
| TF experiment description: | FBXW7 promotes pathological cardiac hypertrophy by targeting EZH2-SIX1 signaling.;FBXW7 promotes pathological cardiac hypertrophy by targeting EZH2-SIX1 signaling.;FBXW7 promotes pathological cardiac hypertrophy by targeting EZH2-SIX1 signaling. |
About Function
| Enhancer function : | FBXW7 promotes pathological cardiac hypertrophy by targeting EZH2-SIX1 signaling. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
FBXW7 promotes pathological cardiac hypertrophy by targeting EZH2-SIX1 signaling. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene