About Enhancer
| Enhancer ID: | E_01_0369 |
| Species: | human |
| Position : | chr3:10139527-10141527   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | -- |
| Pubmed ID: | 30888859 |
| Enhancer experiment: | Western blot, immunofluorescence staining |
| Enhancer experiment description: | Renal cell carcinoma (RCC) is the major cause of death among patients with von Hippel-Lindau (VHL) disease. |
About Target gene
| Target gene : | -- |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Renal cell carcinoma (RCC) is the major cause of death among patients with von Hippel-Lindau (VHL) disease. |
About TF
| TF name : | VHL |
| TF experiment: | Western blot??????? |
| TF experiment description: | Renal cell carcinoma (RCC) is the major cause of death among patients with von Hippel-Lindau (VHL) disease. |
About Function
| Enhancer function : | Renal cell carcinoma (RCC) is the major cause of death among patients with von Hippel-Lindau (VHL) disease. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Renal cell carcinoma (RCC) is the major cause of death among patients with von Hippel-Lindau (VHL) disease. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| VHL | Antigen processing: Ubiquitination & Proteasome degradation | reactome | 260 |
| VHL | HIF-2-alpha transcription factor network | pid | 34 |
| VHL | Hypoxia response via HIF activation | panther | 16 |
| VHL | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha | pid | 19 |
| VHL | Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | reactome | 18 |
| VHL | Pathways in cancer | kegg | 321 |
| VHL | Renal cell carcinoma | kegg | 65 |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene