About Enhancer
| Enhancer ID: | E_01_0356 |
| Species: | human |
| Position : | chr16:67559978-67561978   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | -- |
| Pubmed ID: | 30955885 |
| Enhancer experiment: | Immunofluorescence staining |
| Enhancer experiment description: | Uncoupling DNA demethylation from antisense transcription by Tet3 overexpression in mouse olfactory neurons promotes CTCF binding to all Pcdh? promoters, resulting in proximity-biased DNA looping of the HS5-1 enhancer. |
About Target gene
| Target gene : | -- |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Uncoupling DNA demethylation from antisense transcription by Tet3 overexpression in mouse olfactory neurons promotes CTCF binding to all Pcdh? promoters, resulting in proximity-biased DNA looping of the HS5-1 enhancer. |
About TF
| TF name : | CTCF(MRD21) |
| TF experiment: | ?????? |
| TF experiment description: | Uncoupling DNA demethylation from antisense transcription by Tet3 overexpression in mouse olfactory neurons promotes CTCF binding to all Pcdh? promoters, resulting in proximity-biased DNA looping of the HS5-1 enhancer. |
About Function
| Enhancer function : | Uncoupling DNA demethylation from antisense transcription by Tet3 overexpression in mouse olfactory neurons promotes CTCF binding to all Pcdh? promoters, resulting in proximity-biased DNA looping of the HS5-1 enhancer. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Uncoupling DNA demethylation from antisense transcription by Tet3 overexpression in mouse olfactory neurons promotes CTCF binding to all Pcdh? promoters, resulting in proximity-biased DNA looping of the HS5-1 enhancer. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| CTCF | Activation of anterior HOX genes in hindbrain development during early embryogenesis | reactome | 120 |
| CTCF | TGF_beta_Receptor | netpath | 220 |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene