About Enhancer
| Enhancer ID: | E_01_0329 |
| Species: | human |
| Position : | chr13:27957842-27959842   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | Colon cancer |
| Pubmed ID: | 30631044 |
| Enhancer experiment: | Immunohistochemistry, PCR, Western blot, chip seq |
| Enhancer experiment description: | Caudal-related homeobox transcription factor 2 (CDX2), an intestine-specific nuclear transcription factor, has been strongly implicated in the tumourigenesis of various human cancers. |
About Target gene
| Target gene : | -- |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Caudal-related homeobox transcription factor 2 (CDX2), an intestine-specific nuclear transcription factor, has been strongly implicated in the tumourigenesis of various human cancers. |
About TF
| TF name : | CDX2(CDX-3/AS,CDX3,CDX2) |
| TF experiment: | ???????PCR?Western blot?ChIP-seq |
| TF experiment description: | Caudal-related homeobox transcription factor 2 (CDX2), an intestine-specific nuclear transcription factor, has been strongly implicated in the tumourigenesis of various human cancers. |
About Function
| Enhancer function : | Caudal-related homeobox transcription factor 2 (CDX2), an intestine-specific nuclear transcription factor, has been strongly implicated in the tumourigenesis of various human cancers. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Caudal-related homeobox transcription factor 2 (CDX2), an intestine-specific nuclear transcription factor, has been strongly implicated in the tumourigenesis of various human cancers. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| CDX2 | POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation | reactome | 10 |
| CDX2 | Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | reactome | 20 |
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene