About Enhancer
| Enhancer ID: | E_01_0323 |
| Species: | human |
| Position : | chr22:30922640-30924640   |
| Biosample name: | |
| Experiment class : | High+Lowthroughput |
| Enhancer type: | Enhancer |
| Disease: | -- |
| Pubmed ID: | 30644437 |
| Enhancer experiment: | PCR?Western blot |
| Enhancer experiment description: | Here, we found that MORC2 interacted with TE-III domain of C/EBP?, and the overexpression of MORC2 promoted wild-type C/EBP? sumoylation and its subsequent degradation, which didnt significantly observe in mutant C/EBP?-K161R. |
About Target gene
| Target gene : | MORC2 |
| Strong evidence: | qRT-PCR,qPCR,ChIP,3C |
| Less strong evidence: | RNA-Seq |
| Target gene experiment description: | Here, we found that MORC2 interacted with TE-III domain of C/EBP?, and the overexpression of MORC2 promoted wild-type C/EBP? sumoylation and its subsequent degradation, which didnt significantly observe in mutant C/EBP?-K161R. |
About TF
| TF name : | -- |
| TF experiment: | PCR?Western blot |
| TF experiment description: | Here, we found that MORC2 interacted with TE-III domain of C/EBP?, and the overexpression of MORC2 promoted wild-type C/EBP? sumoylation and its subsequent degradation, which didnt significantly observe in mutant C/EBP?-K161R. |
About Function
| Enhancer function : | Here, we found that MORC2 interacted with TE-III domain of C/EBP?, and the overexpression of MORC2 promoted wild-type C/EBP? sumoylation and its subsequent degradation, which didnt significantly observe in mutant C/EBP?-K161R. |
| Enhancer function experiment: | Immunohistochemical staining |
| Enhancer function experiment description: |
Here, we found that MORC2 interacted with TE-III domain of C/EBP?, and the overexpression of MORC2 promoted wild-type C/EBP? sumoylation and its subsequent degradation, which didnt significantly observe in mutant C/EBP?-K161R. |
About SNP
| SNP ID: | -- |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer associated network
The number on yellow line represents the distance between enhancer and
target gene